
Gresham, Oregon, USA
Sirena grew up around the U.S. and abroad her mother, Margaret Irwin-Brandon, is a harpsichordist and conductor of a Baroque Orchestra, and her father, John Irwin, was a physicist (with a significant stint as a dropped out hippie)-landed ultimately at Sanford University. After time spent at Northfield Mt. Hermon boarding school where she fell in love with theater, she attended San Francisco State University and graduated with degrees in Theater and International Relations. After a successful stint in a popular San Francisco sketch comedy group, she landed in Los Angeles where her knack for voices and accents were quickly put to use in the world of animation. This ultimately brought her to her successful career as a voice director in animation (thanks to her mentor Andrea Romano!) garnering her an Emmy nomination in 2021.

as Cherry-O

as Frida
2004

as Raven
1995

as Cherry-O
1994

as Mera (voice)
2008

as Guard #1 / Old Lady Bug / Poochy (voice)
2022

as Elder Woman / Fly Dancers / Crowd / Dancers (voice)
2021

as Margaret SquarePants (voice)
1999

as The Queen (voice)
2020

as The Eater (voice)
2018

as Reporter / Driver / Ice Cream Lady (voice)
2004

as SpongeBob's Mom / Mowhak Girl / Campers (voice)
2021

as Computer Voice / Shocked Mob Member (voice)
2015

as SpongeBob’s Mom / Gawky Female / The Kid / Office Worker
2019

as Pffht / Various Incidental Characters (voice)
2025

as Lady Upturn / Nurse Helga / Mo / Teen Girls (voice)
2024
as Therapist
2024

as SpongeBob’s Mom / Gawky Female / The Kid / Office Worker
2019

as Harleen Quinzel (voice)
2017

as Miranda Moore (voice)
2016

as Fancy Lady Fish / Kid Fish (voice)
2016

as Computer Voice / Shocked Mob Member (voice)
2015

as Queen Atlanna (voice)
2015

as Additional Voice
2014

as Additional Voices (voice)
2013

as Alura (voice)
2013
as Alisa
2012

as Margret SquarePants
2011

2008

as The Photographer
2007

as Mrs. Palmer (voice)
2006

as Reporter / Driver / Ice Cream Lady (voice)
2004

as Woman Fish
2003

as Beverly
2002

as Gabby
2001
as Cherry-O
1 ep.

as Frida
1 episodes

as Raven
1 episodes

as Cherry-O
1 episodes

as Mera (voice)
2 episodes

as Guard #1 / Old Lady Bug / Poochy (voice)
1 episodes

as Elder Woman / Fly Dancers / Crowd / Dancers (voice)
1 episodes

as Margaret SquarePants (voice)
7 episodes

as The Queen (voice)
1 episodes

as The Eater (voice)
1 episodes

as SpongeBob's Mom / Mowhak Girl / Campers (voice)
1 episodes

as Persephone (voice)
13 episodes

as Cheryl - Tori's Publicist
1 episodes
Casting Director